Acute hypomagnesaemia. Prevention of hypomagnesaemia in patients receiving TPN. Prevention & treatment of life-threatening seizures in treatment of pregnancy toxemias (preeclampsia & eclampsia).
Adult Total dose: Not to exceed 30-40 g daily. Mild hypomagnesaemia 1 g IM every 6 hr for 4 doses. Severe hypomagnesaemia 0.25 g/kg IM over 4 hr or 5 g slow IV infusion over 3 hr. TPN 0.5-3 g daily. Pregnancy toxemia Initially 4 g IV, followed by 4-5 g IM into each buttock or 1-2 g/hr infusion. May be followed by 4-5 g into alternate buttock every 4 hr. Infant TPN 0.25-1.25 g daily.
May precipitate acute myasthenic crisis. Periodically monitor serum Mg levels during therapy & urine output during 4 hr preceding dosing. Determine respiration rate prior to each dose. Test patellar reflex prior to administering repeated dose. Renal impairment. Not to be given during pregnancy 2 hr prior to delivery. Lactation.
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